D-aspartic acid in aged mouse skin and lens.

Gender differences in D-aspartic acid content in skull bone.

In forensic medicine, the personal identification of cadavers is one of the most important tasks. One method of estimating age at death relies on the high correlation between racemization rates in teeth and actual age, and this method has been applied successfully in forensic odontology for several years. In this study, we attempt to facilitate the analysis of racemized amino acids and examine ...

Localization of D- -Aspartic Acid–Containing Proteins in Human Eyes

PURPOSE. Biologically uncommon D-aspartic acid (D-Asp) has been detected in proteins from various human tissues in elderly donors. Previous studies have identified D-Asp residues at four different specific sites in -crystallin from aged human lenses and an increased amount of D-Asp residues with age. D-Asp is formed as a result of racemization and accumulates with age; therefore, it is thought ...

N-methyl-D-aspartic acid receptor structure and function.

Antagonisms in the utilization of d-amino acids by lactic acid bacteria. IV. d-Aspartic acid.

Investigations with glutamic acid, methionine, and alanine have shown that n-amino acid utilization by lactic acid bacteria may be inhibited by specific antimetabolites (l-4). This has been taken to indicate that a conversion of o-amino acid substrate to the L form precedes its utilization, and that this process may be blocked by an appropriate inhibitor. Both Land n-alanines have been shown to...

Biosynthesis of D-Aspartic Acid by Streptococcus faecalis*

In biotin deficiency, aspartic acid becomes a limiting factor in the growth of Streptococcus faecalis ATCC 9190. Suboptimal concentrations of L-aspartate in biotin-deficient medium produce partial growth followed by lysis, which is typical of cell wall lysis due to depletion of an amino acid essential for cell wall biosynthesis. D-Aspartate, which is utilized by the cells with considerable less...